Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | CHAT | P28329 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | IDE | P14735 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | ATIC | P31939 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29363198 | 0.91 | TTR (0.75) | TTRCYP1A2APEX1AURKAAURKB | |
| SCHEMBL6242 | 0.91 | TTR (0.75) | TTRCYP1A2APEX1AURKAAURKB | |
| SCHEMBL30233642 | 0.91 | TTR (0.75) | TTRCYP1A2APEX1AURKAAURKB | |
| Acetic Acid SCHEMBL5230930 | 0.89 | TTR (0.62) | TTRCYP1A2APEX1AURKAAURKB | |
| SCHEMBL2290618 | 0.88 | TTR (0.72) | TTRCYP1A2APEX1AURKAAURKB | |
| SCHEMBL8028660 | 0.88 | TTR (0.72) | TTRCYP1A2APEX1AURKAAURKB | |
| Ammonia Solution, Strong SCHEMBL10954121 | 0.88 | TTR (0.72) | TTRCYP1A2APEX1AURKAAURKB | |
| Lithium SCHEMBL18420655 | 0.88 | TTR (0.72) | TTRCYP1A2APEX1AURKAAURKB | |
| Hydrochloric Acid SCHEMBL7455908 | 0.88 | TTR (0.72) | TTRCYP1A2APEX1AURKAAURKB | |
| SCHEMBL460184 | 0.88 | TTR (0.72) | TTRCYP1A2APEX1AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083293-A1 | PHARMACEUTICALLY ACCEPTABLE SALT OF ELIGLUSTAT AND CRYSTAL FORM THEREOF | 曙方(上海)医药科技有限公司 | 2023-05-19 | — | — | WO | disclosed |