Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL795492 | 1.00 | KMT2A (0.48) | KMT2ABLMALOX15PMP22MAPT | |
| SCHEMBL2518196 | 0.85 | CYP2D6 (0.50) | KMT2ABLMALOX15PMP22MAPT | |
| SCHEMBL3968417 | 0.85 | TSHR (0.47) | KMT2ABLMALOX15PMP22MAPT | |
| SCHEMBL176230 | 0.85 | CYP2D6 (0.50) | KMT2ABLMALOX15PMP22MAPT | |
| SCHEMBL176229 | 0.85 | TSHR (0.47) | KMT2ABLMALOX15PMP22MAPT | |
| SCHEMBL176227 | 0.85 | TSHR (0.47) | KMT2ABLMALOX15PMP22MAPT | |
| SCHEMBL29412215 | 0.84 | BLM (0.44) | KMT2ABLMALOX15PMP22MAPT | |
| SCHEMBL14186824 | 0.84 | TDP1 (0.39) | KMT2ABLMALOX15PMP22MAPT | |
| SCHEMBL10972597 | 0.81 | MAPT (0.42) | KMT2AMAPTCACNA1BAPBA1TSHR | |
| SCHEMBL7950462 | 0.81 | TDP1 (0.39) | KMT2ABLMMAPTCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030513-B2 | Rheology control agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-10-04 | — | — | US | disclosed |
| US-20100204376-A1 | Rheology Control Agents | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2010-08-12 | — | — | US | disclosed |
| US-7741510-B2 | Rheology control agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-22 | — | — | US | disclosed |
| EP-1838749-A1 | COATING COMPOSITIONS CONTAINING RHEOLOGY CONTROL AGENTS | E.I.Du pont de nemours and company (US) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006076715-A1 | COATING COMPOSITIONS CONTAINING RHEOLOGY CONTROL AGENTS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-07-20 | — | — | WO | disclosed |
| US-20060155021-A1 | Coating compositions containing rheology control agents | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-07-13 | — | — | US | disclosed |
| US-20060155146-A1 | Rheology control agents | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060155146-A1 | Rheology control agents | HCRTR1, HCRTR2, REL | KMT2A 2284/4885BLM 1801/4885ALOX15 1500/4885 |
| US-20100204376-A1 | Rheology Control Agents | HCRTR1, HCRTR2, REL | KMT2A 2284/4885BLM 1801/4885ALOX15 1500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.