SCHEMBL25199780

SCHEMBL25199780

COc1ccc(C(=O)/C=C\c2ccc(OC)c(OC)c2)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 9/20 1.00
FLT3 P36888 1/20 1.00
MEN1 O00255 4/20 0.83
KMT2A Q03164 4/20 0.83
MAPT P10636 4/20 0.83
CYP3A4 P08684 3/20 0.83
MAPK1 P28482 3/20 0.83
SMN1; SMN2 Q16637 2/20 0.83
TDP1 Q9NUW8 2/20 0.83
ALDH1A1 P00352 2/20 0.83
TP53 P04637 2/20 0.83
HPGD P15428 2/20 0.83
ALOX15 P16050 2/20 0.83
ALOX12 P18054 1/20 0.83
CTSL P07711 2/20 0.80
PDE4A P27815 1/20 0.78
PDE4B Q07343 1/20 0.78
PDE4C Q08493 1/20 0.78
PDE4D Q08499 1/20 0.78
APP P05067 5/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5082183 1.00 ABCG2 (1.00) ABCG2FLT3MEN1KMT2AMAPT
SCHEMBL30382948 1.00 ABCG2 (1.00) ABCG2FLT3MEN1KMT2AMAPT
SCHEMBL30384406 1.00 ABCG2 (1.00) ABCG2FLT3MEN1KMT2AMAPT
SCHEMBL5082179 1.00 ABCG2 (1.00) ABCG2FLT3MEN1KMT2AMAPT
SCHEMBL31233013 0.92 ABCG2 (0.85) ABCG2FLT3MEN1KMT2AMAPT
SCHEMBL21527689 0.92 ABCG2 (0.85) ABCG2FLT3MEN1KMT2AMAPT
SCHEMBL21527682 0.92 ABCG2 (0.85) ABCG2FLT3MEN1KMT2AMAPT
SCHEMBL21527688 0.92 ABCG2 (0.85) ABCG2FLT3MEN1KMT2AMAPT
SCHEMBL21527681 0.92 ABCG2 (0.85) ABCG2FLT3MEN1KMT2AMAPT
SCHEMBL25234197 0.92 ABCG2 (0.85) ABCG2FLT3MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ABCG2 1606/4885FLT3 1462/4885MEN1 3367/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885FLT3 2207/4885MEN1 2457/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885FLT3 2207/4885MEN1 2457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.