SCHEMBL25199791

SCHEMBL25199791

COc1ccc(C(=O)C=Cc2cccc(OCCC(=O)O)c2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.73
BCHE P06276 3/20 0.65
CYP1B1 Q16678 2/20 0.62
TNFRSF1A P19438 2/20 0.62
MEN1 O00255 1/20 0.62
ALDH1A1 P00352 1/20 0.62
MAPT P10636 1/20 0.62
HSPD1 P10809 1/20 0.62
HSPE1 P61604 1/20 0.62
KMT2A Q03164 1/20 0.62
CYP1A1 P04798 1/20 0.58
CYP1A2 P05177 1/20 0.58
CYP2D6 P10635 1/20 0.58
KEAP1 Q14145 1/20 0.57
NFE2L2 Q16236 1/20 0.57
F3 P13726 1/20 0.56
CYP3A4 P08684 2/20 0.55
NFKB1 P19838 1/20 0.55
NFKB2 Q00653 1/20 0.55
RELA Q04206 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25201561 1.00 MAOB (0.73) MAOBBCHECYP1B1TNFRSF1AMEN1
SCHEMBL30382795 1.00 MAOB (0.73) MAOBBCHECYP1B1TNFRSF1AMEN1
SCHEMBL30382942 1.00 MAOB (0.73) MAOBBCHECYP1B1TNFRSF1AMEN1
SCHEMBL30383204 0.90 MAOB (0.71) MAOBBCHECYP1B1TNFRSF1AMEN1
SCHEMBL25207818 0.90 MAOB (0.71) MAOBBCHECYP1B1TNFRSF1AMEN1
SCHEMBL25229347 0.89 BCHE (0.65) MAOBBCHECYP1B1TNFRSF1AALDH1A1
SCHEMBL31233116 0.89 BCHE (0.65) MAOBBCHECYP1B1TNFRSF1AALDH1A1
SCHEMBL30383438 0.89 BCHE (0.65) MAOBBCHECYP1B1TNFRSF1AALDH1A1
SCHEMBL25218020 0.89 BCHE (0.65) MAOBBCHECYP1B1TNFRSF1AALDH1A1
SCHEMBL25195492 0.88 BCHE (0.59) MAOBBCHECYP1B1MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAOB 1004/4885BCHE 588/4885CYP1B1 230/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885BCHE 465/4885CYP1B1 1027/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885BCHE 465/4885CYP1B1 1027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.