SCHEMBL2520032

SCHEMBL2520032

C=CCOC(=O)C(N)C(C)CC

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.40
TSHR P16473 1/20 0.40
DPP4 P27487 11/20 0.39
DPP8 Q6V1X1 7/20 0.39
DPP9 Q86TI2 7/20 0.39
MAPT P10636 1/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
IARS1 P41252 3/20 0.35
DPP7 Q9UHL4 6/20 0.35
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3965568 1.00 TDP1 (0.40) TDP1TSHRDPP4DPP8DPP9
Hydrochloric Acid SCHEMBL8565446 0.98 TDP1 (0.39) TDP1TSHRDPP4DPP8DPP9
Hydrochloric Acid SCHEMBL8565445 0.98 TDP1 (0.39) TDP1TSHRDPP4DPP8DPP9
SCHEMBL10458429 0.92 TDP1 (0.36) TDP1TSHRDPP4DPP8DPP9
SCHEMBL2730560 0.82 TDP1 (0.43) TDP1TSHRDPP4MAPTCACNA1B
SCHEMBL2519765 0.82 TDP1 (0.43) TDP1TSHRDPP4MAPTCACNA1B
SCHEMBL27587694 0.82 TDP1 (0.38) TDP1TSHRMAPTCACNA1BAPBA1
SCHEMBL5135717 0.81 TDP1 (0.42) TDP1TSHRMAPTCACNA1BAPBA1
SCHEMBL1162237 0.81 TDP1 (0.42) TDP1TSHRMAPTCACNA1BAPBA1
SCHEMBL2521938 0.81 TDP1 (0.42) TDP1TSHRMAPTCACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8030513-B2 Rheology control agents E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-10-04 US disclosed
US-20100204376-A1 Rheology Control Agents AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2010-08-12 US disclosed
US-7741510-B2 Rheology control agents E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-22 US disclosed
US-7589170-B1 Synthesis of cyclic peptides THE UNIVERSITY OF QUEENSLAND (AU) 2009-09-15 US disclosed
EP-1838749-A1 COATING COMPOSITIONS CONTAINING RHEOLOGY CONTROL AGENTS E.I.Du pont de nemours and company (US) 2007-10-03 EP disclosed
WO-2006076715-A1 COATING COMPOSITIONS CONTAINING RHEOLOGY CONTROL AGENTS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-07-20 WO disclosed
US-20060155021-A1 Coating compositions containing rheology control agents E. I. DU PONT DE NEMOURS AND COMPANY 2006-07-13 US disclosed
US-20060155146-A1 Rheology control agents AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2006-07-13 US disclosed
EP-1115738-A4 SYNTHESIS OF CYCLIC PEPTIDES UNIV QUEENSLAND (AU) 2004-09-01 EP disclosed
EP-1115738-A1 SYNTHESIS OF CYCLIC PEPTIDES THE UNIVERSITY OF QUEENSLAND (AU) 2001-07-18 EP disclosed
WO-2000018790-A1 SYNTHESIS OF CYCLIC PEPTIDES THE UNIVERSITY OF QUEENSLAND (AU) 2000-04-06 WO disclosed
US-4977272-A Radiation absorbers THE STANDARD OIL COMPANY (US) 1990-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060155146-A1 Rheology control agents HCRTR1, HCRTR2, REL TDP1 2448/4885TSHR 839/4885DPP4 4816/4885
US-20100204376-A1 Rheology Control Agents HCRTR1, HCRTR2, REL TDP1 2448/4885TSHR 839/4885DPP4 4816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.