Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 11/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | IARS1 | P41252 | 3/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2520032 | 1.00 | TDP1 (0.40) | TDP1TSHRDPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL8565446 | 0.98 | TDP1 (0.39) | TDP1TSHRDPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL8565445 | 0.98 | TDP1 (0.39) | TDP1TSHRDPP4DPP8DPP9 | |
| SCHEMBL10458429 | 0.92 | TDP1 (0.36) | TDP1TSHRDPP4DPP8DPP9 | |
| SCHEMBL2730560 | 0.82 | TDP1 (0.43) | TDP1TSHRDPP4MAPTCACNA1B | |
| SCHEMBL2519765 | 0.82 | TDP1 (0.43) | TDP1TSHRDPP4MAPTCACNA1B | |
| SCHEMBL27587694 | 0.82 | TDP1 (0.38) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL5135717 | 0.81 | TDP1 (0.42) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL1162237 | 0.81 | TDP1 (0.42) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL2521938 | 0.81 | TDP1 (0.42) | TDP1TSHRMAPTCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589170-B1 | Synthesis of cyclic peptides | THE UNIVERSITY OF QUEENSLAND (AU) | 2009-09-15 | — | — | US | disclosed |
| EP-1115738-A4 | SYNTHESIS OF CYCLIC PEPTIDES | UNIV QUEENSLAND (AU) | 2004-09-01 | — | — | EP | disclosed |
| EP-1115738-A1 | SYNTHESIS OF CYCLIC PEPTIDES | THE UNIVERSITY OF QUEENSLAND (AU) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018790-A1 | SYNTHESIS OF CYCLIC PEPTIDES | THE UNIVERSITY OF QUEENSLAND (AU) | 2000-04-06 | — | — | WO | disclosed |
| EP-0605434-B1 | IMIDAZO (4,5-C) PYRIDINE DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIOTECH PHARM (GB) | 1998-08-19 | — | — | EP | disclosed |
| US-5563151-A | PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS; ANTIINFLAMMATORY AGENTS, ANALGESICS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| US-5446032-A | Platelet activsating factor antagonist | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-08-29 | — | — | US | disclosed |
| EP-0623116-A1 | AMINO ACID DERIVATIVES AS PAF-RECEPTOR ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| EP-0605434-A1 | IMIDAZO (4,5-C) PYRIDINE DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1994-07-13 | — | — | EP | disclosed |
| WO-1993014072-A1 | AMINO ACID DERIVATIVES AS PAF-RECEPTOR ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |
| WO-1993002080-A1 | IMIDAZO (4,5-C) PYRIDINE DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-02-04 | — | — | WO | disclosed |
| US-4977272-A | Radiation absorbers | THE STANDARD OIL COMPANY (US) | 1990-12-11 | — | — | US | disclosed |