Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.71 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.71 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.70 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27881565 | 0.92 | GABRA1 (0.60) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL3847939 | 0.89 | GABRA1 (0.73) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL18589529 | 0.85 | GABRA1 (0.68) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL7284420 | 0.84 | GABRA1 (0.78) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL30417619 | 0.84 | GABRA1 (0.78) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL2939048 | 0.84 | HSD17B10 (0.81) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL28289133 | 0.83 | GABRA1 (0.65) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL11273297 | 0.83 | GABRA1 (0.65) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL7291769 | 0.83 | GABRA1 (1.00) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL7381114 | 0.82 | GABRA1 (1.00) | GABRA1GABRB2GABRB1GABRA3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113845476-B | Quinolone derivative and preparation method and application thereof | 中国药科大学 | 2024-04-30 | — | — | CN | disclosed |
| WO-2023077739-A1 | QUINOLONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 中国药科大学 | 2023-05-11 | — | — | WO | disclosed |
| WO-2023077739-A1 | QUINOLONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 中国药科大学 | 2023-05-11 | — | — | WO | disclosed |
| CN-113845476-A | Quinolone derivative and preparation method and application thereof | 中国药科大学 | 2021-12-28 | — | — | CN | disclosed |