SCHEMBL2520116

SCHEMBL2520116

CC(C)(C)CC(C(=O)OCC(COC(=O)C(CC(C)(C)C)c1ccc(O)c(C(C)(C)C)c1)(COC(=O)C(CC(C)(C)C)c1ccc(O)c(C(C)(C)C)c1)COC(=O)C(CC(C)(C)C)c1ccc(O)c(C(C)(C)C)c1)c1ccc(O)c(C(C)(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.40
GAA P10253 1/20 0.40
XBP1 P17861 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 3/20 0.38
NR1I2 O75469 1/20 0.38
LMNA P02545 1/20 0.38
CYP2C9 P11712 1/20 0.38
MIF P14174 1/20 0.38
TYR P14679 1/20 0.38
ALOX15 P16050 1/20 0.38
HTT P42858 1/20 0.38
NFE2L2 Q16236 1/20 0.38
HSD17B10 Q99714 1/20 0.38
HSP90AA1 P07900 4/20 0.38
HSP90AB1 P08238 4/20 0.38
ESRRA P11474 2/20 0.37
NR1H4 Q96RI1 4/20 0.35
RARB P10826 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28853653 0.88 ATM (0.43) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL1871824 0.86 ATM (0.41) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL10916916 0.85 ATM (0.39) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL29141758 0.84 ATM (0.40) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL28115085 0.84 L3MBTL1 (0.51) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL11229437 0.84 ATM (0.38) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL11227080 0.84 ATM (0.38) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL30979216 0.82 ATM (0.42) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL5401921 0.82 ATM (0.39) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL5417452 0.82 ATM (0.39) ATMGAAXBP1NPSR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0392392-B1 Method for stabilizing polyolefins CIBA GEIGY AG (CH) 1995-12-06 EP claimed
EP-2210918-B1 RESIN COMPOSITION AND RESIN MOLDED ARTICLE ADEKA CORP (JP) 2015-01-14 EP disclosed
EP-2204420-B1 SYNTHETIC RESIN COMPOSITION AND AUTOMOTIVE INTERIOR/EXTERIOR MATERIAL ADEKA CORP (JP) 2013-03-20 EP disclosed
US-8034856-B2 Synthetic resin composition and automotive interior/exterior material ADEKA CORPORATION (JP) 2011-10-11 US disclosed
US-20100249288-A1 SYNTHETIC RESIN COMPOSITION AND AUTOMOTIVE INTERIOR/EXTERIOR MATERIAL ADEKA CORPORATION (JP) 2010-09-30 US disclosed
US-20100249289-A1 RESIN COMPOSITION AND RESIN MOLDED ARTICLE ADEKA CORPORATION (JP) 2010-09-30 US disclosed
EP-2210918-A1 RESIN COMPOSITION AND RESIN MOLDED ARTICLE Adeka Corporation (JP) 2010-07-28 EP disclosed
EP-2204420-A1 SYNTHETIC RESIN COMPOSITION AND AUTOMOTIVE INTERIOR/EXTERIOR MATERIAL Adeka Corporation (JP) 2010-07-07 EP disclosed
US-5401845-A Asymmetric aryl phosphites CIBA-GEIGY CORPORATION (US) 1995-03-28 US disclosed
US-5340855-A Stabilizer for polymers CIBA-GEIGY CORPORATION (US) 1994-08-23 US disclosed
US-5322871-A Stabilize polymers against oxidation, thermal and photodegradation CIBA-GEIGY CORPORATION (US) 1994-06-21 US disclosed
US-5240622-A Mixture of a polymer, a lubricant, a metal working fluid or a hydraulic fluid and thermal, oxidative and/or actinic radiation stabilizer CIBA-GEIGY CORPORATION (US) 1993-08-31 US disclosed
US-5239076-A Processing stabilizer for polyethylene and polypropylene CIBA-GEIGY CORPORATION (US) 1993-08-24 US disclosed
US-5175312-A Radiation resistance CIBA-GEIGY CORPORATION (US) 1992-12-29 US disclosed
US-5132387-A Polyme bound ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-07-21 US disclosed
EP-0494639-A2 Hindered amine light stabilizer hydrazides for stabilizing polyurethane, polyurea and polyurethane-polyurea polymers ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-07-15 EP disclosed
EP-0016123-A4 IMPROVED REINFORCED THERMOPLASTIC MOLDING COMPOSITIONS. GEN ELECTRIC (US) 1980-11-14 EP disclosed
EP-0016123-A1 IMPROVED REINFORCED THERMOPLASTIC MOLDING COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1980-10-01 EP disclosed
WO-1980000255-A1 IMPROVED REINFORCED THERMOPLASTIC MOLDING COMPOSITIONS GEN ELECTRIC (US) 1980-02-21 WO disclosed