SCHEMBL25201218

SCHEMBL25201218

O=C(/C=C/c1ccccc1)c1c(O)cc(O)cc1OC1O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC28A3 Q9HAS3 4/20 0.64
▸ AKR1B1 P15121 1/20 0.61
▸ DPP4 P27487 1/20 0.61
▸ SLC5A1 P13866 5/20 0.58
▸ HPGD P15428 2/20 0.58
▸ HSD17B10 Q99714 2/20 0.58
▸ MAPT P10636 2/20 0.58
▸ SLC5A2 P31639 2/20 0.58
▸ KDM4E B2RXH2 1/20 0.58
▸ CYP3A4 P08684 1/20 0.58
▸ THRB P10828 1/20 0.58
▸ CYP2C9 P11712 1/20 0.58
▸ CYP2C19 P33261 1/20 0.58
▸ SLC28A2 O43868 1/20 0.58
▸ EPHX2 P34913 1/20 0.58
▸ MEN1 O00255 1/20 0.56
▸ KCNA3 P22001 1/20 0.56
▸ KMT2A Q03164 1/20 0.56
▸ NPSR1 Q6W5P4 1/20 0.56
▸ GAA P10253 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30384588 1.00 SLC28A3 (0.64) SLC28A3AKR1B1DPP4SLC5A1HPGD
SCHEMBL25208547 1.00 SLC28A3 (0.64) SLC28A3AKR1B1DPP4SLC5A1HPGD
SCHEMBL25189140 0.93 AKR1B1 (0.68) SLC28A3AKR1B1DPP4SLC5A1HPGD
SCHEMBL25195723 0.93 AKR1B1 (0.68) SLC28A3AKR1B1DPP4SLC5A1HPGD
SCHEMBL25209554 0.93 AKR1B1 (0.68) SLC28A3AKR1B1DPP4SLC5A1HPGD
SCHEMBL25191306 0.93 AKR1B1 (0.68) SLC28A3AKR1B1DPP4SLC5A1HPGD
SCHEMBL25202960 0.93 AKR1B1 (0.68) SLC28A3AKR1B1DPP4SLC5A1HPGD
SCHEMBL25189358 0.93 AKR1B1 (0.68) SLC28A3AKR1B1DPP4SLC5A1HPGD
SCHEMBL25214843 0.93 AKR1B1 (0.68) SLC28A3AKR1B1DPP4SLC5A1HPGD
SCHEMBL25192695 0.93 AKR1B1 (0.68) SLC28A3AKR1B1DPP4SLC5A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B SLC28A3 3901/4885AKR1B1 2220/4885DPP4 4226/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 SLC28A3 4577/4885AKR1B1 2215/4885DPP4 3670/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 SLC28A3 4577/4885AKR1B1 2215/4885DPP4 3670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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