SCHEMBL25201264

SCHEMBL25201264

NNC(=O)C1=CC=CNC=C1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
MPO P05164 2/20 0.31
CYP3A4 P08684 2/20 0.31
BLM P54132 2/20 0.31
P2RX7 Q99572 1/20 0.31
KDM5A P29375 1/20 0.31
GFER P55789 1/20 0.31
PMP22 Q01453 1/20 0.31
HIF1A Q16665 1/20 0.31
KDM4E B2RXH2 3/20 0.31
ALDH1A1 P00352 2/20 0.31
LMNA P02545 2/20 0.31
MAPT P10636 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
NSD2 O96028 1/20 0.31
ALPL P05186 1/20 0.31
POLB P06746 1/20 0.31
ALPI P09923 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7390867 0.82 HDAC3 (0.30) CA1CA9
SCHEMBL27293804 0.78
SCHEMBL531906 0.78
Water SCHEMBL27527439 0.76
Hydrochloric Acid SCHEMBL27880977 0.76
SCHEMBL1238252 0.75
Hydrochloric Acid SCHEMBL28600502 0.74
Water SCHEMBL27651933 0.74
SCHEMBL1986899 0.74
Benzene SCHEMBL27686426 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023088420-A1 1H-BENZO[B]AZEPIN-2(3H)-ONE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER Chengdu Anticancer Bioscience, Ltd. (CN) 2023-05-25 WO disclosed