⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27527439 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL27880977 | 0.98 | — | — | |
| SCHEMBL28299873 | 0.83 | — | — | |
| SCHEMBL7854382 | 0.80 | — | — | |
| SCHEMBL1238252 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL28600502 | 0.78 | — | — | |
| Water SCHEMBL27651933 | 0.78 | — | — | |
| SCHEMBL1986899 | 0.78 | — | — | |
| Benzene SCHEMBL27686426 | 0.78 | — | — | |
| SCHEMBL25201264 | 0.78 | CA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994010-A | Method for synthesizing oxcarbazepine key intermediate | 衢州市浙工大生态工业创新研究院 | 2024-11-22 | — | — | CN | claimed |
| CN-106588773-B | A kind of Brain targeting eslicarbazepine ester prodrug and its application | 北京现代药物代谢研究院 | 2019-09-27 | — | — | CN | claimed |
| CN-108101844-A | The preparation method of 10,11- dihydros -10 oxo -5H- dibenzo [b, f] azepine * -5- formamides | 常州沃腾化工科技有限公司 | 2018-06-01 | — | — | CN | claimed |
| CN-106588773-A | Brain-targeting eslicarbazepine ester prodrug and application thereof | 北京现代药物代谢研究院 | 2017-04-26 | — | — | CN | claimed |
| CN-104910072-A | 8-substituted benzoazepines as TOLL-like receptor modulators | ARRAY BIOPHARMA INC | 2015-09-16 | — | — | CN | claimed |
| CN-104803915-A | 8-substituted benzoazepines as toll-like receptor modulators | ARRAY BIOPHARMA INC | 2015-07-29 | — | — | CN | claimed |
| WO-2012156987-A2 | A NOVEL PROCESS FOR THE PREPARATION OF ESLICARBAZEPINE | GLENMARK GENERICS LIMITED (IN) | 2012-11-22 | — | — | WO | claimed |
| EP-1915346-B1 | ASYMMETRIC CATALYTIC REDUCTION OF OXCARBAZEPINE | BIAL PORTELA & CA SA (PT) | 2011-08-17 | — | — | EP | claimed |
| CN-1511141-B | 10, 11-dihydro-10-hydroxy-5H-dibenzo [ b, f ] azepine-5-carboxamide and process for preparing 10, 11-dihydro-10-oxo-5H-dibenzo [ b, f ] azepine-5-carboxamide | PORTELA & CA SA | 2011-06-08 | — | — | CN | claimed |
| US-20100173893-A1 | Preparation of eslicarbazepine and related compounds by asymmetric hydrogenation | BIAL - PORTELA & C.A., S.A. | 2010-07-08 | — | — | US | claimed |
| EP-1385826-A1 | METHOD FOR PREPARATION OF (S)-(+)- AND (R)-(-)-10,11-DIHYDRO-10-HYDROXY-5H-DIBENZ/B,F/AZEPINE-5-CARBOXAMIDE | Portela & CA SA (PT) | 2004-02-04 | — | — | EP | claimed |
| WO-2002092572-A1 | METHOD FOR PREPARATION OF (S)-(+)- AND (R)-(-)-10,11-DIHYDRO-10-HYDROXY-5H-DIBENZ/B,F/AZEPINE-5-CARBOXAMIDE | PORTELA & CA SA (PT) | 2002-11-21 | — | — | WO | claimed |
| EP-0751129-B1 | Substituted dihydrodibenzo(b,f)azepines, method for their preparation, their use in the treatment of some central nervous system disorders, and pharmaceutical compositions containing them | PORTELA & CA SA (PT) | 1998-11-18 | — | — | EP | claimed |
| CN-1038128-C | Process for manufacture of N,N-(dibenzohexatrienylene) ureas | CIBA GEIGY AG (CH) | 1998-04-22 | — | — | CN | claimed |
| US-5695782-A | Double-layered oxcarbazepine tablets | CIBA GEIGY CORPORATION (US) | 1997-12-09 | — | — | US | claimed |
| WO-1997045416-A1 | NEW DERIVATIVES OF 10,11-DIHYDRO-10-OXO-5H-DIBENZ/b,F/AZEPINE-5-CARBOXAMIDE | PORTELA & CA. S.A. (PT) | 1997-12-04 | — | — | WO | claimed |
| EP-0751129-A1 | Substituted dihydrodibenzo/b, f/azepines, method for their preparation, their use in the treatment of some central nervous system disorders, and pharmaceutical compositions containing them | Portela & Ca., S.A. (PT) | 1997-01-02 | — | — | EP | claimed |
| CN-1039018-A | N, the preparation method of N-(the inferior second triolefin of dibenzo) urea | CIBA GEIGY AG (CH) | 1990-01-24 | — | — | CN | claimed |
| EP-0029409-B1 | PROCESS FOR PREPARING 5-CYANO-5H-DIBENZ(B,F)AZEPINE AND 5H-DIBENZ(B,F)AZEPINE-5-CARBOXAMIDE | CIBA-GEIGY AG (CH) | 1984-08-15 | — | — | EP | claimed |
| EP-0108715-A1 | Dibenzazepine carboxamides | CIBA-GEIGY AG (CH) | 1984-05-16 | — | — | EP | claimed |