SCHEMBL25201510

SCHEMBL25201510

CCC(=O)[Si](OC)(C(=O)CC)C(=O)CC

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
ALDH1A1 P00352 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
FFAR3 O14843 1/20 0.35
EPHX1 P07099 1/20 0.34
MGAM O43451 2/20 0.33
GAA P10253 2/20 0.33
SI P14410 2/20 0.33
MGAM2 Q2M2H8 2/20 0.33
HSD17B10 Q99714 1/20 0.33
SOAT1 P35610 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ALOX15 P16050 1/20 0.31
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL583363 0.77 FFAR3 (0.42) TSHRALDH1A1TDP1FFAR3SOAT1
SCHEMBL25199497 0.74 TDP1 (0.33) ALDH1A1TDP1FFAR3SOAT1
SCHEMBL16773726 0.70
SCHEMBL12928869 0.69 ALDH1A1 (0.39) TSHRALDH1A1MGAMGAASI
SCHEMBL25364748 0.67 ALDH1A1 (0.37) TSHRALDH1A1TDP1FFAR3HSD17B10
SCHEMBL14941367 0.65 TSHR (0.38) TSHRALDH1A1MGAMGAASI
SCHEMBL3288569 0.65
SCHEMBL4617907 0.65 ALDH1A1 (0.41) TSHRALDH1A1FFAR3MGAMGAA
SCHEMBL15434 0.65
SCHEMBL14760146 0.65 ALDH1A1 (0.41) TSHRALDH1A1TDP1FFAR3SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023201138-A1 PREPARATION OF POLYETHER-FUNCTIONAL ORGANOSILICON COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-10-19 WO disclosed
WO-2023183682-A1 PREPARATION OF ORGANOSILICON COMPOUNDS WITH CARBOXY FUNCTIONALITY DOW GLOBAL TECHNOLOGIES LLC (US) 2023-09-28 WO disclosed
WO-2023091868-A2 PREPARATION OF ORGANOSILICON COMPOUNDS WITH CARBINOL FUNCTIONALITY DOW GLOBAL TECHNOLOGIES LLC (US) 2023-05-25 WO disclosed