SCHEMBL25201664

SCHEMBL25201664

O=C(C=Cc1ccc(OCc2cc(OCc3cc(OCc4ccccc4)cc(OCc4ccccc4)c3)cc(OCc3cc(OCc4ccccc4)cc(OCc4ccccc4)c3)c2)cc1)c1ccc(OCc2cc(OCc3cc(OCc4ccccc4)cc(OCc4ccccc4)c3)cc(OCc3cc(OCc4ccccc4)cc(OCc4ccccc4)c3)c2)cc1O

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.79
SLC5A1 P13866 1/20 0.67
SLC5A2 P31639 1/20 0.67
ABCG2 Q9UNQ0 2/20 0.63
MAOB P27338 8/20 0.60
GSK3B P49841 3/20 0.60
BACE1 P56817 3/20 0.60
MAPT P10636 2/20 0.59
NPC1 O15118 1/20 0.59
LMNA P02545 1/20 0.59
RECQL P46063 1/20 0.59
RAB9A P51151 1/20 0.59
ATM Q13315 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
MAOA P21397 1/20 0.57
KDM4E B2RXH2 1/20 0.57
MEN1 O00255 1/20 0.57
TP53 P04637 1/20 0.57
KMT2A Q03164 1/20 0.57
CYSLTR2 Q9NS75 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31232996 1.00 APP (0.79) APPSLC5A1SLC5A2ABCG2MAOB
SCHEMBL25201663 1.00 APP (0.79) APPSLC5A1SLC5A2ABCG2MAOB
SCHEMBL25285074 0.95 APP (0.86) APPSLC5A1SLC5A2ABCG2MAOB
SCHEMBL20169867 0.95 APP (0.86) APPSLC5A1SLC5A2ABCG2MAOB
SCHEMBL25196413 0.95 APP (0.86) APPSLC5A1SLC5A2ABCG2MAOB
SCHEMBL25199799 0.92 APP (0.80) APPSLC5A1SLC5A2ABCG2MAOB
SCHEMBL10829591 0.92 APP (0.80) APPSLC5A1SLC5A2ABCG2MAOB
SCHEMBL25191246 0.92 APP (0.80) APPSLC5A1SLC5A2ABCG2MAOB
SCHEMBL14692632 0.91 APP (0.83) APPSLC5A1SLC5A2ABCG2MAOB
SCHEMBL14692633 0.91 APP (0.83) APPSLC5A1SLC5A2ABCG2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B APP 794/4885SLC5A1 3752/4885SLC5A2 4208/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 APP 1340/4885SLC5A1 4485/4885SLC5A2 4756/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 APP 1340/4885SLC5A1 4485/4885SLC5A2 4756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.