Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 15/20 | 0.55 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.42 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2517361 | 0.83 | BDKRB1 (0.64) | BDKRB1 | |
| SCHEMBL2521908 | 0.82 | BDKRB1 (0.71) | BDKRB1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2516768 | 0.79 | BDKRB1 (0.70) | BDKRB1 | |
| SCHEMBL2516340 | 0.78 | BDKRB1 (0.81) | BDKRB1 | |
| SCHEMBL2516339 | 0.78 | BDKRB1 (0.81) | BDKRB1 | |
| SCHEMBL2520326 | 0.78 | BDKRB1 (0.59) | BDKRB1 | |
| SCHEMBL2516990 | 0.77 | BDKRB1 (0.60) | BDKRB1 | |
| SCHEMBL2520202 | 0.76 | BDKRB1 (0.53) | BDKRB1 | |
| SCHEMBL2516994 | 0.75 | BDKRB1 (0.58) | BDKRB1 | |
| Hydrochloric Acid SCHEMBL2525420 | 0.75 | BDKRB1 (0.60) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034827-B2 | Phenanthridine derivatives as bradykinin antagonists | Richter Gegeon Nyrt. (HU) | 2011-10-11 | — | — | US | disclosed |