Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 18/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2516994 | 0.79 | BDKRB1 (0.58) | BDKRB1CYP3A4GAACYP2C19 | |
| SCHEMBL2518523 | 0.78 | BDKRB1 (0.55) | BDKRB1CYP3A4GAACYP2C19 | |
| SCHEMBL2517774 | 0.78 | BDKRB1 (0.55) | BDKRB1CYP3A4GAACYP2C19 | |
| SCHEMBL2516990 | 0.78 | BDKRB1 (0.60) | BDKRB1 | |
| SCHEMBL2516340 | 0.77 | BDKRB1 (0.81) | BDKRB1 | |
| SCHEMBL2516339 | 0.77 | BDKRB1 (0.81) | BDKRB1 | |
| SCHEMBL2521908 | 0.76 | BDKRB1 (0.71) | BDKRB1CYP3A4CYP2C19 | |
| SCHEMBL2520201 | 0.76 | BDKRB1 (0.55) | BDKRB1 | |
| SCHEMBL2520245 | 0.72 | BDKRB1 (0.51) | BDKRB1 | |
| Hydrochloric Acid SCHEMBL2525420 | 0.72 | BDKRB1 (0.60) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034827-B2 | Phenanthridine derivatives as bradykinin antagonists | Richter Gegeon Nyrt. (HU) | 2011-10-11 | — | — | US | disclosed |