Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29612272 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL15303089 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL29612298 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL29612261 | 0.90 | BRD4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL29564499 | 0.89 | PDCD1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL2525982 | 0.89 | PDCD1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL8633278 | 0.87 | CA12 (0.33) | — | |
| Hydrochloric Acid SCHEMBL3213459 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL29612271 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL29612284 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2033975-B1 | Catalyst composition | BASELL POLYOLEFINE GMBH (DE) | 2014-05-14 | — | — | EP | disclosed |
| US-8039569-B2 | Polyethylene molding compositions for injection molding applications | BASELL POLYOLEFINE GMBH (DE) | 2011-10-18 | — | — | US | disclosed |
| EP-1874830-B1 | MOLDING COMPOSITION COMPRISING POLYETHYLENE FOR PREPARING FILMS AND PROCESS FOR PREPARING THE MOLDING COMPOSITION IN THE PRESENCE OF A MIXED CATALYST | BASELL POLYOLEFINE GMBH (DE) | 2010-10-20 | — | — | EP | disclosed |
| US-7799722-B2 | Catalyst system for the polymerization of olefin | BASELL POLYOLEFINE GMBH (DE) | 2010-09-21 | — | — | US | disclosed |
| US-20090311453-A1 | Molding compostion comprsing polyethlene for preparing films and process for preparing the molding composition in the presence of a mixed catalyst | BASELL POLYOLEFINE GMBH (DE) | 2009-12-17 | — | — | US | disclosed |
| US-20090306324-A1 | Polyethylene molding compositions for injection molding applications | BASELL POLYOLEFINE GMBH (DE) | 2009-12-10 | — | — | US | disclosed |
| US-7541481-B2 | Monocyclopentadienyl complex | BASELL POLYOLEFIN GMBH (DE) | 2009-06-02 | — | — | US | disclosed |
| US-7507782-B2 | Transition-metal complexes with tridentate, nitrogen-containing ligands | BASELL POLYOLEFINE GMBH (DE) | 2009-03-24 | — | — | US | disclosed |
| EP-2033975-A1 | Catalyst composition | Basell Polyolefine GmbH (DE) | 2009-03-11 | — | — | EP | disclosed |
| EP-1874831-B1 | POLYETHYLENE MOLDING COMPOSITIONS FOR INJECTION MOLDING APPLICATIONS | BASELL POLYOLEFINE GMBH (DE) | 2008-12-03 | — | — | EP | disclosed |
| EP-1625168-A1 | TRANSITION-METAL COMPLEXES WITH TRIDENTATE, NITROGEN-CONTAINING LIGANDS | Basell Polyolefine GmbH (DE) | 2006-02-15 | — | — | EP | disclosed |
| EP-1613671-A1 | PROCESS FOR PREPARING POROUS POLYMERS AND POLYMERS THEREOF | Basell Polyolefine GmbH (DE) | 2006-01-11 | — | — | EP | disclosed |
| US-20060004215-A1 | Monocyclopentadienyl complexes | EQUISTAR CHEMICALS, LP | 2006-01-05 | — | — | US | disclosed |
| WO-2005095468-A2 | CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2005-10-13 | — | — | WO | disclosed |
| EP-1539774-A1 | MONOCYCLOPENTADIENYL COMPLEXES | Basell Polyolefine GmbH (DE) | 2005-06-15 | — | — | EP | disclosed |
| EP-1534724-A2 | MONOCYCLOPENTADIENYL COMPLEXES | Basell Polyolefine GmbH (DE) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004104052-A1 | TRANSITION-METAL COMPLEXES WITH TRIDENTATE, NITROGEN-CONTAINING LIGANDS | BASELL POLYOLEFINE GMBH (DE) | 2004-12-02 | — | — | WO | disclosed |
| WO-2004092230-A1 | PROCESS FOR PREPARING POROUS POLYMERS AND POLYMERS THEREOF | BASELL POLYOLEFINE GMBH (DE) | 2004-10-28 | — | — | WO | disclosed |
| WO-2004020479-A2 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2004-03-11 | — | — | WO | disclosed |
| WO-2004018489-A1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2004-03-04 | — | — | WO | disclosed |