SCHEMBL25205245

SCHEMBL25205245

Cn1cc(-c2ccc(N3CCN(C(=O)O)C(C(C)(C)C)C3)nc2)cn1

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RET P07949 20/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22631102 0.85 RET (0.67) RET
SCHEMBL22631009 0.83 RET (0.71) RET
SCHEMBL28569603 0.83 RET (0.43) RET
SCHEMBL22638185 0.81 ME2 (0.51)
SCHEMBL25273965 0.80 GRM1 (0.43)
SCHEMBL3554487 0.77 CHRM4 (0.51)
SCHEMBL26620008 0.76 MEN1 (0.55)
SCHEMBL22631088 0.74 RET (0.68) RET
SCHEMBL5652856 0.74 GRIN2D (0.42)
SCHEMBL21981500 0.74 PANK3 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118055933-A Selective PARP1 inhibitors and uses thereof 成都百裕制药股份有限公司 2024-05-17 CN disclosed
WO-2023088408-A1 SELECTIVE PARP1 INHIBITOR AND APPLICATION THEREOF 成都百裕制药股份有限公司 2023-05-25 WO disclosed