SCHEMBL25206400

SCHEMBL25206400

COC(=O)c1n[nH]c2cccc(Br)c2c1=O

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 0.55
▸ STAT3 P40763 1/20 0.55
▸ HIF1A Q16665 1/20 0.55
▸ FLT3 P36888 3/20 0.41
▸ LRRK2 Q5S007 1/20 0.40
▸ MAPT P10636 2/20 0.39
▸ F2 P00734 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ KDM4C Q9H3R0 1/20 0.39
▸ SMN1; SMN2 Q16637 4/20 0.39
▸ YTHDC1 Q96MU7 1/20 0.38
▸ CDK2 P24941 1/20 0.37
▸ NR4A2 P43354 1/20 0.36
▸ CDC7 O00311 1/20 0.36
▸ FEN1 P39748 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2599805 0.91 KDM4E (0.60) KDM4ESTAT3HIF1AFLT3LRRK2
SCHEMBL25205501 0.85 KDM4E (0.58) KDM4ESTAT3HIF1AMAPTKMT2A
SCHEMBL2071431 0.83 KDM4E (0.55) KDM4ESTAT3HIF1AFLT3LRRK2
SCHEMBL27998212 0.77 KDM4E (0.41) KDM4ESTAT3HIF1AFLT3YTHDC1
SCHEMBL1967918 0.76 GPR17 (0.43) KDM4ESTAT3HIF1AFLT3YTHDC1
SCHEMBL7737920 0.75 KDM4E (0.59) KDM4ESTAT3HIF1AFLT3LRRK2
SCHEMBL4791540 0.75 KDM4E (0.59) KDM4ESTAT3HIF1AFLT3LRRK2
SCHEMBL14271999 0.75 KDM4E (0.59) KDM4ESTAT3HIF1AFLT3LRRK2
SCHEMBL2862825 0.75 KDM4E (0.59) KDM4ESTAT3HIF1AFLT3LRRK2
SCHEMBL28503864 0.74 KDM4E (0.57) KDM4ESTAT3HIF1AFLT3LRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313549-A1 HERBICIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2025-10-09 — — US disclosed
EP-4433467-A1 HERBICIDAL DERIVATIVES Syngenta Crop Protection AG (CH) 2024-09-25 — — EP disclosed
CN-118265705-A Herbicidal derivatives 先正达农作物保护股份公司 2024-06-28 — — CN disclosed
WO-2023088921-A1 HERBICIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2023-05-25 — — WO disclosed
WO-2023088921-A1 HERBICIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2023-05-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313549-A1 HERBICIDAL DERIVATIVES DDT, CYP1B1, CYP1A1 KDM4E 834/4885STAT3 4863/4885HIF1A 1545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback