SCHEMBL25207663

SCHEMBL25207663

COc1ccc(C=CC(=O)c2ccc(O)cc2)cc1COc1ccc(Cl)cc1

nearest known ligand 0.81

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 5/20 0.81
▸ KMT2A Q03164 5/20 0.81
▸ LMNA P02545 5/20 0.81
▸ ALDH1A1 P00352 3/20 0.81
▸ KDM4E B2RXH2 3/20 0.81
▸ ABCG2 Q9UNQ0 3/20 0.65
▸ MAPT P10636 5/20 0.63
▸ THRB P10828 1/20 0.63
▸ SMN1; SMN2 Q16637 1/20 0.63
▸ CXCL12 P48061 2/20 0.61
▸ CXCR4 P61073 1/20 0.61
▸ CTSL P07711 1/20 0.58
▸ MAOB P27338 4/20 0.58
▸ MAOA P21397 1/20 0.58
▸ P4HB P07237 1/20 0.56
▸ CALM1 P0DP23 1/20 0.56
▸ RAB9A P51151 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31233297 1.00 MEN1 (0.81) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25234254 1.00 MEN1 (0.81) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL31233173 1.00 MEN1 (0.81) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25198797 0.92 MEN1 (0.86) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25195235 0.90 MEN1 (0.82) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL30382681 0.90 MEN1 (0.78) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25208719 0.90 MEN1 (0.78) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL31233303 0.90 MEN1 (0.71) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25205516 0.90 MEN1 (0.71) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25219934 0.90 MEN1 (0.78) MEN1KMT2ALMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MEN1 3367/4885KMT2A 2792/4885LMNA 1180/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MEN1 2457/4885KMT2A 3188/4885LMNA 1817/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MEN1 2457/4885KMT2A 3188/4885LMNA 1817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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