Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ABL1 | P00519 | 2/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.41 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30473945 | 0.94 | KDM4E (0.49) | KDM4EGAAKMT2AABL1BRAF | |
| SCHEMBL14968582 | 0.84 | SCN9A (0.53) | GAAABL1BRAFLCLAT1SCN9A | |
| SCHEMBL25213511 | 0.83 | ALDH1A1 (0.57) | KDM4EGAAKMT2AABL1PIM1 | |
| SCHEMBL25211630 | 0.83 | GAA (0.52) | KDM4EGAAKMT2APIM1IGF2BP2 | |
| SCHEMBL1795070 | 0.82 | ALDH1A1 (0.44) | ABL1BRAFPIM1LCLAT1FFAR1 | |
| SCHEMBL30468358 | 0.82 | CHEK1 (0.47) | KDM4EGAAKMT2AABL1BRAF | |
| SCHEMBL13407882 | 0.82 | CHEK1 (0.47) | KDM4EGAAKMT2AABL1BRAF | |
| SCHEMBL25240945 | 0.82 | ABL1 (0.47) | KDM4EABL1BRAFLCLAT1FFAR1 | |
| SCHEMBL25213585 | 0.81 | CA1 (0.54) | KDM4EGAAKMT2AMAPTMEN1 | |
| SCHEMBL17478821 | 0.81 | ABL1 (0.45) | KDM4EKMT2AABL1BRAFLCLAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302422-A | Substituted N-cyanopyrrolidines having activity as USP30 inhibitors | 特殊治疗有限公司 | 2024-07-05 | — | — | CN | disclosed |
| WO-2023099561-A1 | SUBSTITUTED N-CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS | MISSION THERAPEUTICS LIMITED (GB) | 2023-06-08 | — | — | WO | disclosed |