Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18493061 | 0.74 | TP53 (0.37) | TP53MAPTNPC1ALDH1A1XBP1 | |
| SCHEMBL25417470 | 0.72 | TP53 (0.36) | TP53MAPTNPC1ALDH1A1XBP1 | |
| SCHEMBL12143311 | 0.72 | NPC1 (0.42) | TP53MAPTNPC1ALDH1A1XBP1 | |
| SCHEMBL5352223 | 0.68 | LMNA (0.47) | TP53MAPTNPC1ALDH1A1XBP1 | |
| SCHEMBL31022027 | 0.68 | CA1 (0.45) | LMNAL3MBTL1 | |
| SCHEMBL10646837 | 0.68 | MAPT (0.46) | TP53MAPTNPC1ALDH1A1XBP1 | |
| SCHEMBL830120 | 0.67 | — | — | |
| SCHEMBL8380272 | 0.67 | — | — | |
| SCHEMBL805467 | 0.67 | PARP1 (0.50) | TP53MAPTNPC1ALDH1A1XBP1 | |
| SCHEMBL12547362 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023084449-A1 | DIAMINOCYCLOPENTYLPYRIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE OR DISORDER | NOVARTIS AG (CH) | 2023-05-19 | — | — | WO | disclosed |