SCHEMBL25211808

SCHEMBL25211808

COCC12CCC(CNC1)N2C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25415541 1.00 DPP4 (0.30) DPP4
SCHEMBL30392573 0.90
SCHEMBL30392136 0.86 DPP4 (0.33) DPP4
SCHEMBL30520662 0.86 DPP4 (0.30) DPP4
SCHEMBL25327796 0.84 DPP4 (0.34) DPP4
SCHEMBL25413586 0.84
SCHEMBL30520607 0.84
SCHEMBL25216428 0.83 CHRM2 (0.38)
SCHEMBL25414973 0.82
SCHEMBL25416974 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023244713-A1 QUINAZOLINE DERIVATIVES, COMPOSITIONS AND METHODS THEREOF ENSEM THERAPEUTICS, INC. (US) 2023-12-21 WO disclosed
WO-2023173014-A1 KRAS INHIBITORS AND THEIR USE BLOSSOMHILL THERAPEUTICS, INC. (US) 2023-09-14 WO disclosed
WO-2023098425-A1 KRAS INHIBITORS, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF 上海和誉生物医药科技有限公司 2023-06-08 WO disclosed