Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25211808 | 0.86 | DPP4 (0.30) | DPP4 | |
| SCHEMBL25415541 | 0.86 | DPP4 (0.30) | DPP4 | |
| SCHEMBL30520607 | 0.84 | — | — | |
| SCHEMBL25413586 | 0.84 | — | — | |
| SCHEMBL30392573 | 0.82 | — | — | |
| SCHEMBL25414973 | 0.80 | — | — | |
| SCHEMBL25416974 | 0.80 | — | — | |
| SCHEMBL29937133 | 0.79 | — | — | |
| SCHEMBL30520662 | 0.78 | DPP4 (0.30) | DPP4 | |
| SCHEMBL3822469 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118055932-A | KRAS inhibitor and preparation and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2024-05-17 | — | — | CN | disclosed |
| WO-2023098425-A1 | KRAS INHIBITORS, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 上海和誉生物医药科技有限公司 | 2023-06-08 | — | — | WO | disclosed |