SCHEMBL25213631

SCHEMBL25213631

O=S(=O)(NCc1ccc2[nH]ccc2c1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 8/20 0.54
NPC1 O15118 1/20 0.52
ALDH1A1 P00352 2/20 0.50
MAPT P10636 2/20 0.50
PKM P14618 1/20 0.50
CA12 O43570 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA9 Q16790 2/20 0.49
MEN1 O00255 1/20 0.47
THRB P10828 1/20 0.47
RECQL P46063 1/20 0.47
KMT2A Q03164 1/20 0.47
KEAP1 Q14145 1/20 0.47
KDM1A O60341 1/20 0.46
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
CYP19A1 P11511 2/20 0.46
PIK3CD O00329 1/20 0.46
MMP1 P03956 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25249850 0.90 CNR1 (0.51) CNR1ALDH1A1MAPTPKMCA12
SCHEMBL25217311 0.87 ALDH1A1 (0.48) CNR1ALDH1A1MAPTPKMCA12
SCHEMBL25250699 0.85 CYP19A1 (0.59) CNR1ALDH1A1MAPTMEN1THRB
SCHEMBL25270169 0.85 ALDH1A1 (0.69) CNR1ALDH1A1MAPTCA12CA9
SCHEMBL25247183 0.85 CYP19A1 (0.59) CNR1ALDH1A1MAPTPKMMEN1
SCHEMBL25212820 0.85 CYP19A1 (0.59) CNR1ALDH1A1MAPTPKMCA1
SCHEMBL25212567 0.81 CYP19A1 (0.62) CNR1ALDH1A1MAPTCA1CA2
SCHEMBL25250703 0.81 CYP19A1 (0.62) CNR1ALDH1A1MAPTPKMTHRB
SCHEMBL25266935 0.81 CYP19A1 (0.62) ALDH1A1MAPTCA1CA2MEN1
SCHEMBL25221451 0.80 POLB (0.50) CNR1ALDH1A1MAPTPKMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250093329-A1 SCREENING OF COMPOUNDS THE UNIVERSITY OF TULSA 2025-03-20 US disclosed
EP-4469592-A1 SCREENING OF COMPOUNDS The University Of Tulsa (US) 2024-12-04 EP disclosed
US-20230266302-A1 SYNTHESIS AND USE OF N-BENZYL SULFONAMIDES THE UNIV OF TULSA (US) 2023-08-24 US disclosed
WO-2023146904-A1 SCREENING OF COMPOUNDS THE UNIVERSITY OF TULSA (US) 2023-08-03 WO disclosed
EP-4185706-A1 SYNTHESIS AND USE OF N-BENZYL SULFONAMIDES The University Of Tulsa (US) 2023-05-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230266302-A1 SYNTHESIS AND USE OF N-BENZYL SULFONAMIDES ATP5ME, ATP5F1B, ATP5MG CNR1 1972/4885NPC1 584/4885ALDH1A1 1210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.