Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOGAT2 | Q3SYC2 | 3/20 | 0.43 |
| ▸ | RORC | P51449 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30471003 | 1.00 | MOGAT2 (0.43) | MOGAT2RORCKMT2ATP53LMNA | |
| SCHEMBL31528389 | 0.94 | IDO1 (0.43) | MOGAT2RORCKMT2ATP53LMNA | |
| SCHEMBL30471098 | 0.92 | RORC (0.41) | MOGAT2RORCKMT2ATP53LMNA | |
| SCHEMBL25244085 | 0.92 | RORC (0.41) | MOGAT2RORCKMT2ATP53LMNA | |
| SCHEMBL30471234 | 0.88 | ESR1 (0.50) | MOGAT2KMT2AGAAUSP2ALDH1A1 | |
| SCHEMBL25590650 | 0.88 | ESR1 (0.50) | MOGAT2KMT2AGAAUSP2ALDH1A1 | |
| SCHEMBL25215175 | 0.86 | GAA (0.43) | MOGAT2RORCKMT2AGAAUSP2 | |
| SCHEMBL25247343 | 0.86 | MOGAT2 (0.44) | MOGAT2KMT2AGAAUSP2ALDH1A1 | |
| SCHEMBL30471047 | 0.86 | GAA (0.43) | MOGAT2RORCKMT2AGAAUSP2 | |
| SCHEMBL30471164 | 0.86 | MOGAT2 (0.44) | MOGAT2KMT2AGAAUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023094828-A1 | ANTAGONISTS OF CAV 2.3 | LARIO THERAPEUTICS LIMITED (GB) | 2023-06-01 | — | — | WO | disclosed |
| WO-2023094828-A1 | ANTAGONISTS OF CAV 2.3 | LARIO THERAPEUTICS LIMITED (GB) | 2023-06-01 | — | — | WO | disclosed |