Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.62 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25915192 | 0.91 | TMPRSS2 (0.57) | TMPRSS2IRAK4ADORA3ADORA2AADORA2B | |
| SCHEMBL23959988 | 0.88 | TMPRSS2 (0.66) | TMPRSS2 | |
| SCHEMBL24106482 | 0.87 | TMPRSS2 (0.67) | TMPRSS2ADORA3ADORA1 | |
| SCHEMBL26004234 | 0.85 | TMPRSS2 (0.62) | TMPRSS2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL30960132 | 0.84 | TMPRSS2 (0.71) | TMPRSS2 | |
| SCHEMBL30363087 | 0.83 | TMPRSS2 (0.59) | TMPRSS2 | |
| SCHEMBL30973741 | 0.82 | TMPRSS2 (0.66) | TMPRSS2 | |
| Gs-441524 SCHEMBL24975226 | 0.82 | TMPRSS2 (0.60) | TMPRSS2ADORA2AHIF1A | |
| Gs-441524 SCHEMBL22663744 | 0.82 | TMPRSS2 (0.60) | TMPRSS2ADORA2AHIF1A | |
| Gs-441524 SCHEMBL22096285 | 0.82 | TMPRSS2 (0.60) | TMPRSS2ADORA2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102472-A1 | ANTIVIRAL PRODRUGS AND FORMULATIONS THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-06-08 | — | — | WO | disclosed |