Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.62 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26002360 | 0.93 | TMPRSS2 (0.54) | TMPRSS2MAP4K4ADORA2AADORA3ADORA1 | |
| SCHEMBL26001888 | 0.91 | TMPRSS2 (0.53) | TMPRSS2MAP4K4KDM4EMEN1NPC1 | |
| SCHEMBL24106482 | 0.89 | TMPRSS2 (0.67) | TMPRSS2MAP4K4ADORA3ADORA1 | |
| SCHEMBL23959988 | 0.88 | TMPRSS2 (0.66) | TMPRSS2 | |
| SCHEMBL30973747 | 0.87 | TMPRSS2 (0.66) | TMPRSS2 | |
| SCHEMBL26206741 | 0.86 | TMPRSS2 (0.66) | TMPRSS2 | |
| SCHEMBL25216402 | 0.85 | TMPRSS2 (0.62) | TMPRSS2ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL25318315 | 0.84 | TMPRSS2 (0.66) | TMPRSS2 | |
| SCHEMBL24789766 | 0.84 | TMPRSS2 (0.66) | TMPRSS2 | |
| SCHEMBL12393420 | 0.84 | TMPRSS2 (0.58) | TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230263900-A1 | DENDRIMER-DRUG CONJUGATE | STARPHARMA PTY LTD (AU) | 2023-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230263900-A1 | DENDRIMER-DRUG CONJUGATE | SARS1, MMAB, PAM | TMPRSS2 68/4885MAP4K4 2527/4885ADORA2A 1023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.