Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 11/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30473978 | 0.97 | HDAC1 (0.46) | HDAC1HDAC6GRIN1GRIN2BCYP2C9 | |
| SCHEMBL24073262 | 0.90 | HDAC1 (0.48) | HDAC1HDAC6GRIN1GRIN2BCYP2C9 | |
| SCHEMBL31017693 | 0.90 | HDAC1 (0.48) | HDAC1HDAC6GRIN1GRIN2BCYP2C9 | |
| SCHEMBL25236309 | 0.89 | HDAC1 (0.38) | HDAC1HDAC6KCNH2 | |
| Trifluoroacetic Acid SCHEMBL30371030 | 0.87 | HDAC1 (0.46) | HDAC1HDAC6GRIN1GRIN2BCYP2C9 | |
| Trifluoroacetic Acid SCHEMBL30473949 | 0.86 | FAAH (0.42) | HDAC1HDAC6 | |
| Trifluoroacetic Acid SCHEMBL30473991 | 0.86 | HDAC1 (0.37) | HDAC1HDAC6 | |
| SCHEMBL25215130 | 0.86 | FAAH (0.44) | HDAC1HDAC6 | |
| SCHEMBL24073650 | 0.84 | HDAC1 (0.51) | HDAC1HDAC6GRIN1GRIN2BCYP2C9 | |
| SCHEMBL25838522 | 0.84 | HDAC1 (0.51) | HDAC1HDAC6GRIN1GRIN2BCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023099561-A1 | SUBSTITUTED N-CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS | MISSION THERAPEUTICS LIMITED (GB) | 2023-06-08 | — | — | WO | disclosed |