Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3059967 | 1.00 | L3MBTL1 (0.41) | L3MBTL1RAB9AMAPTHCRTR2ALDH1A1 | |
| SCHEMBL29584483 | 0.88 | MEN1 (0.43) | RAB9AMAPTHCRTR2ALDH1A1GAA | |
| SCHEMBL18586063 | 0.88 | MEN1 (0.43) | RAB9AMAPTHCRTR2ALDH1A1GAA | |
| SCHEMBL18345004 | 0.86 | SCN9A (0.49) | SCN9A | |
| SCHEMBL6694621 | 0.86 | SCN9A (0.49) | SCN9A | |
| SCHEMBL5459736 | 0.86 | SCN9A (0.49) | SCN9A | |
| SCHEMBL4760197 | 0.86 | SCN9A (0.49) | SCN9A | |
| SCHEMBL4436548 | 0.86 | SCN9A (0.49) | SCN9A | |
| SCHEMBL6690206 | 0.85 | SMN1; SMN2 (0.46) | RAB9ASMN1; SMN2NPC1KDM1A | |
| SCHEMBL6690204 | 0.85 | SMN1; SMN2 (0.46) | RAB9ASMN1; SMN2NPC1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102477-A1 | PERIPHERALLY AND LUMINALLY-RESTRICTED INHIBITORS OF THE SEROTONIN TRANSPORTER AS TREATMENTS FOR DISORDERS OF GASTROINTESTINAL MOTILITY | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-06-08 | — | — | WO | disclosed |