SCHEMBL25219005

SCHEMBL25219005

Cc1ccc(S(=O)(=O)NCc2coc(C)n2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.58
MEN1 O00255 2/20 0.58
TP53 P04637 5/20 0.53
POLB P06746 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.52
LMNA P02545 1/20 0.52
HTT P42858 1/20 0.52
CA12 O43570 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
ATM Q13315 1/20 0.51
CA9 Q16790 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
ALDH1A1 P00352 3/20 0.50
MAPT P10636 2/20 0.50
CYP19A1 P11511 1/20 0.50
KDM4E B2RXH2 1/20 0.49
THRB P10828 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9561776 0.76 KMT2A (0.61) KMT2AMEN1SMN1; SMN2LMNAHTT
SCHEMBL5010826 0.75 SMN1; SMN2 (0.54) KMT2AMEN1SMN1; SMN2LMNAHTT
SCHEMBL25547142 0.72 CA12 (0.83) KMT2AMEN1TP53SMN1; SMN2LMNA
SCHEMBL29530578 0.72 PRMT1 (0.74) KMT2AMEN1POLBSMN1; SMN2LMNA
SCHEMBL9305676 0.72 PRMT1 (0.74) KMT2AMEN1POLBSMN1; SMN2LMNA
SCHEMBL5009915 0.71 LMNA (0.52) KMT2AMEN1SMN1; SMN2LMNAHTT
SCHEMBL25254452 0.71 KMT2A (0.62) KMT2AMEN1SMN1; SMN2LMNAHTT
SCHEMBL25267360 0.71 LMNA (0.60) KMT2AMEN1SMN1; SMN2LMNAHTT
SCHEMBL21875079 0.70 KLKB1 (0.48) KMT2AMEN1TP53POLBALDH1A1
SCHEMBL13297941 0.70 KMT2A (0.91) KMT2AMEN1POLBSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250093329-A1 SCREENING OF COMPOUNDS THE UNIVERSITY OF TULSA 2025-03-20 US disclosed
EP-4469592-A1 SCREENING OF COMPOUNDS The University Of Tulsa (US) 2024-12-04 EP disclosed
US-20230266302-A1 SYNTHESIS AND USE OF N-BENZYL SULFONAMIDES THE UNIV OF TULSA (US) 2023-08-24 US disclosed
WO-2023146904-A1 SCREENING OF COMPOUNDS THE UNIVERSITY OF TULSA (US) 2023-08-03 WO disclosed
EP-4185706-A1 SYNTHESIS AND USE OF N-BENZYL SULFONAMIDES The University Of Tulsa (US) 2023-05-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230266302-A1 SYNTHESIS AND USE OF N-BENZYL SULFONAMIDES ATP5ME, ATP5F1B, ATP5MG KMT2A 1813/4885MEN1 3299/4885TP53 1437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.