Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 5/20 | 0.43 |
| ▸ | NPY1R | P25929 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 2/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005035 | 0.95 | NPY4R (0.43) | NPY4RNPY1RALOX15MEN1CYP1A2 | |
| SCHEMBL13949746 | 0.95 | NPY4R (0.43) | NPY4RNPY1RALOX15MEN1CYP1A2 | |
| SCHEMBL23048407 | 0.95 | NPY4R (0.43) | NPY4RNPY1RALOX15MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7302869 | 0.94 | NPY4R (0.43) | NPY4RNPY1RALOX15MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL28825330 | 0.94 | NPY4R (0.43) | NPY4RNPY1RALOX15MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7303864 | 0.94 | NPY4R (0.43) | NPY4RNPY1RALOX15MEN1CYP1A2 | |
| SCHEMBL10676657 | 0.85 | TDP1 (0.42) | MEN1KMT2ACA1CA2 | |
| SCHEMBL16263594 | 0.85 | NPY4R (0.49) | NPY4RNPY1RFOLH1NPY2RNPY5R | |
| SCHEMBL8663352 | 0.84 | FOLH1 (0.43) | NPY4RNPY1RALOX15MEN1CYP1A2 | |
| SCHEMBL350358 | 0.84 | FOLH1 (0.43) | NPY4RNPY1RALOX15MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364166-A1 | SUPPRESSION OF CANCER | Syntaxin Limited (GB) | 2011-09-14 | — | — | EP | disclosed |
| WO-2010055358-A1 | SUPPRESSION OF CANCER | SYNTAXIN LIMITED (GB) | 2010-05-20 | — | — | WO | disclosed |