Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13863591 | 0.86 | MEN1 (0.42) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL2521911 | 0.85 | NPY4R (0.43) | KMT2AMEN1CA1CA2 | |
| SCHEMBL8666247 | 0.85 | MEN1 (0.40) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL25455532 | 0.84 | KMT2A (0.56) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL3693813 | 0.82 | MEN1 (0.41) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL12234273 | 0.82 | TDP1 (0.41) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL13949746 | 0.81 | NPY4R (0.43) | KMT2AMEN1CA1CA2 | |
| SCHEMBL23048407 | 0.81 | NPY4R (0.43) | KMT2AMEN1CA1CA2 | |
| SCHEMBL8005035 | 0.81 | NPY4R (0.43) | KMT2AMEN1CA1CA2 | |
| SCHEMBL16263608 | 0.80 | MEN1 (0.44) | TDP1ATMNPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |