Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3112772 | 0.80 | ESR2 (0.45) | ESR2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL1700775 | 0.79 | NCF1 (0.38) | PLGPLATLMNANCF1CYP3A4 | |
| SCHEMBL25309654 | 0.79 | PLG (0.35) | PLGPLATLMNANCF1CYP3A4 | |
| SCHEMBL25309658 | 0.79 | PLG (0.35) | PLGPLATLMNANCF1CYP3A4 | |
| SCHEMBL10635038 | 0.78 | PLG (0.38) | PLGPLATLMNANCF1CYP3A4 | |
| SCHEMBL12424264 | 0.76 | POLB (0.46) | ESR2 | |
| SCHEMBL2707090 | 0.76 | NCF1 (0.35) | PLGPLATLMNANCF1CYP3A4 | |
| SCHEMBL13240744 | 0.75 | ESR2 (0.45) | ESR2 | |
| SCHEMBL11497497 | 0.75 | PLG (0.39) | PLGPLATLMNANCF1CYP3A4 | |
| SCHEMBL12525042 | 0.75 | ESR2 (0.45) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104043-A1 | ANTI-APOPTOTIC PROTEIN BCL-2 INHIBITOR, PHARMACEUTICAL COMPOSITION AND USES THEREOF | 杭州和正医药有限公司 | 2023-06-15 | — | — | WO | disclosed |