Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.43 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25650723 | 1.00 | SCD (0.43) | SCDTAS2R8AAK1KDM4EHPGD | |
| SCHEMBL25275107 | 1.00 | SCD (0.43) | SCDTAS2R8AAK1KDM4EHPGD | |
| SCHEMBL25270623 | 0.90 | SCD (0.41) | SCDTAS2R8AAK1KDM4EHPGD | |
| SCHEMBL30489288 | 0.90 | SCD (0.41) | SCDTAS2R8AAK1KDM4EHPGD | |
| SCHEMBL25270622 | 0.90 | SCD (0.41) | SCDTAS2R8AAK1KDM4EHPGD | |
| SCHEMBL30489228 | 0.88 | SCD (0.44) | SCDTAS2R8KDM4EHPGDUSP2 | |
| SCHEMBL25270627 | 0.88 | SCD (0.44) | SCDTAS2R8KDM4EHPGDUSP2 | |
| SCHEMBL25225604 | 0.88 | SCD (0.44) | SCDTAS2R8KDM4EHPGDUSP2 | |
| SCHEMBL25650722 | 0.86 | TAS2R8 (0.44) | SCDTAS2R8KDM4EHPGDUSP2 | |
| SCHEMBL25650671 | 0.85 | SCD (0.43) | SCDTAS2R8KDM4EHPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023111181-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2023-06-22 | — | — | WO | disclosed |