Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.67 |
| ▸ | HTR2A | P28223 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 3/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.52 |
| ▸ | HTR3B | O95264 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 1/20 | 0.52 |
| ▸ | HTR1E | P28566 | 1/20 | 0.52 |
| ▸ | HTR1F | P30939 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25275014 | 0.92 | HTR6 (0.60) | HTR6HTR2AKMT2AMEN1HTR2B | |
| SCHEMBL25226887 | 0.92 | HTR6 (0.56) | HTR6HTR2AKMT2AMEN1HTR2B | |
| Mebufotenin SCHEMBL31079539 | 0.89 | HTR2A (0.67) | HTR6HTR2AKMT2AHTR2BMTNR1A | |
| SCHEMBL25272783 | 0.89 | HTR6 (0.75) | HTR6HTR2AKMT2AMEN1HTR2B | |
| Mebufotenin SCHEMBL22800102 | 0.89 | HTR2A (0.67) | HTR6HTR2AKMT2AHTR2BMTNR1A | |
| SCHEMBL25227976 | 0.85 | HTR6 (0.52) | HTR6HTR2AKMT2AMEN1HTR2B | |
| SCHEMBL2002124 | 0.82 | HTR6 (0.74) | HTR6HTR2AKMT2AMEN1HTR2B | |
| SCHEMBL29445016 | 0.82 | HTR6 (0.74) | HTR6HTR2AKMT2AMEN1HTR2B | |
| SCHEMBL25230814 | 0.82 | HTR6 (0.45) | HTR6HTR2AKMT2AMEN1HTR2B | |
| SCHEMBL25225176 | 0.81 | HTR6 (0.64) | HTR6HTR2AKMT2AMEN1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023108174-A1 | ANALOGS OF 6-METHOXY- N, N-DIMETHYLTRYPTAMINE | TERRAN BIOSCIENCES, INC. (US) | 2023-06-15 | — | — | WO | disclosed |