Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 12/20 | 0.61 |
| ▸ | IKZF1 | Q13422 | 5/20 | 0.57 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.55 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31077305 | 1.00 | IKZF2 (0.61) | IKZF2IKZF1CRBNGSPT1CYP2C19 | |
| SCHEMBL25647442 | 0.93 | IKZF2 (0.56) | IKZF2IKZF1CRBNGSPT1CYP2C19 | |
| SCHEMBL31077350 | 0.93 | IKZF2 (0.59) | IKZF2IKZF1CRBNGSPT1DDB1 | |
| SCHEMBL25230212 | 0.93 | IKZF2 (0.59) | IKZF2IKZF1CRBNGSPT1DDB1 | |
| SCHEMBL30459997 | 0.92 | IKZF2 (0.64) | IKZF2IKZF1CRBNGSPT1DDB1 | |
| SCHEMBL24817833 | 0.92 | IKZF2 (0.64) | IKZF2IKZF1CRBNGSPT1DDB1 | |
| SCHEMBL25280964 | 0.89 | IKZF2 (0.53) | IKZF2IKZF1CRBNGSPT1CYP2C19 | |
| SCHEMBL31076750 | 0.89 | IKZF2 (0.53) | IKZF2IKZF1CRBNGSPT1CYP2C19 | |
| SCHEMBL31077479 | 0.88 | IKZF2 (0.59) | IKZF2IKZF1CRBNGSPT1CYP2C19 | |
| SCHEMBL25647412 | 0.88 | IKZF2 (0.59) | IKZF2IKZF1CRBNGSPT1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | claimed |
| CN-116239566-A | E3 ubiquitin ligase ligand compound, protein degradation agent developed based on ligand compound and application thereof | 标新生物医药科技(上海)有限公司 | 2023-06-09 | — | — | CN | claimed |
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |