Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 9/20 | 0.64 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.61 |
| ▸ | IKZF1 | Q13422 | 5/20 | 0.60 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.54 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.54 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24817833 | 1.00 | IKZF2 (0.64) | IKZF2CRBNIKZF1GSPT1DDB1 | |
| SCHEMBL31077305 | 0.92 | IKZF2 (0.61) | IKZF2CRBNIKZF1GSPT1DDB1 | |
| SCHEMBL25227367 | 0.92 | IKZF2 (0.61) | IKZF2CRBNIKZF1GSPT1DDB1 | |
| SCHEMBL30790518 | 0.92 | IKZF1 (0.65) | IKZF2CRBNIKZF1 | |
| SCHEMBL30458571 | 0.92 | IKZF2 (0.62) | IKZF2CRBNIKZF1GSPT1DDB1 | |
| Trifluoroacetic Acid SCHEMBL31372295 | 0.92 | IKZF2 (0.60) | IKZF2CRBNIKZF1GSPT1DDB1 | |
| SCHEMBL30459793 | 0.91 | IKZF2 (0.65) | IKZF2CRBNIKZF1 | |
| SCHEMBL31077350 | 0.90 | IKZF2 (0.59) | IKZF2CRBNIKZF1GSPT1DDB1 | |
| SCHEMBL25230212 | 0.90 | IKZF2 (0.59) | IKZF2CRBNIKZF1GSPT1DDB1 | |
| SCHEMBL25647442 | 0.90 | IKZF2 (0.56) | IKZF2CRBNIKZF1GSPT1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581025-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | Auron Therapeutics, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| CN-117881668-A | Compound based on isoindoline substituted glutarimide skeleton and application thereof | 标新生物医药科技(上海)有限公司 | 2024-04-12 | — | — | CN | disclosed |
| WO-2024050078-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | AURON THERAPEUTICS, INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| WO-2023230059-A1 | MDM2 DEGRADER | NEWAVE PHARMACEUTICAL INC. (US) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |