Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25538211 | 0.85 | BTK (0.50) | — | |
| SCHEMBL30398110 | 0.85 | BTK (0.50) | — | |
| SCHEMBL13873845 | 0.76 | EPHX2 (0.61) | HPGDRECQLMEN1KMT2ATSHR | |
| SCHEMBL13160339 | 0.75 | EPHX2 (0.54) | HPGDRECQLMEN1KMT2ATSHR | |
| SCHEMBL13873816 | 0.74 | PRMT5 (0.50) | HPGDRECQLMEN1KMT2ATSHR | |
| SCHEMBL13873834 | 0.74 | EPHX2 (0.58) | HPGDRECQLMEN1KMT2ATSHR | |
| SCHEMBL1312845 | 0.72 | TP53 (0.56) | HPGDRECQLMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13125273 | 0.72 | POLB (0.54) | HPGDRECQLMEN1KMT2ATSHR | |
| SCHEMBL1313160 | 0.72 | SMN1; SMN2 (0.56) | HPGDMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL13621178 | 0.72 | SMN1; SMN2 (0.56) | HPGDMEN1KMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |