Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 3/20 | 0.71 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.71 |
| ▸ | STS | P08842 | 4/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 2/20 | 0.56 |
| ▸ | AR | P10275 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.56 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412522 | 0.91 | ABCC4 (0.72) | ABCC4ABCC1STSCYP2C9SLCO1B1 | |
| SCHEMBL3232321 | 0.90 | ESR1 (0.70) | ABCC4ABCC1STSCYP2C9KDM4E | |
| SCHEMBL5521870 | 0.90 | ABCC4 (0.76) | ABCC4ABCC1STSCYP2C9SLCO1B1 | |
| SCHEMBL2517551 | 0.90 | ABCC4 (0.76) | ABCC4ABCC1STSCYP2C9SLCO1B1 | |
| Estradiol Disulfate SCHEMBL231199 | 0.83 | ABCC4 (1.00) | ABCC4ABCC1STSCYP2C9SLCO1B1 | |
| SCHEMBL29392632 | 0.83 | ABCC4 (1.00) | ABCC4ABCC1STSCYP2C9SLCO1B1 | |
| SCHEMBL232796 | 0.83 | ABCC4 (1.00) | ABCC4ABCC1STSCYP2C9SLCO1B1 | |
| SCHEMBL232797 | 0.83 | ABCC4 (1.00) | ABCC4ABCC1STSCYP2C9SLCO1B1 | |
| SCHEMBL30471686 | 0.83 | ABCC4 (1.00) | ABCC4ABCC1STSCYP2C9SLCO1B1 | |
| SCHEMBL345570 | 0.82 | STS (0.71) | ABCC1STSCYP2C9KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110250274-A1 | ESTRIOL FORMULATIONS | EVESTRA, INC. | 2011-10-13 | — | — | US | disclosed |
| WO-2010033832-A2 | ESTRIOL FORMULATIONS | EVESTRA, INC. (US) | 2010-03-25 | — | — | WO | disclosed |
| US-20070243217-A1 | Film-Shaped Medicament for Oral Administration Containing Estriol | HF ARZNEIMITTELFORSCHUNG GMBH (DE) | 2007-10-18 | — | — | US | disclosed |
| EP-1761242-A2 | FILM-SHAPED ESTRIOL-CONTAINING MEDICAMENT FOR ORAL ADMINISTRATION | HF Arzneimittelforschung GmbH (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2005110358-A2 | FILM-SHAPED ESTRIOL-CONTAINING MEDICAMENT FOR ORAL ADMINISTRATION | HF ARZNEIMITTELFORSCHUNG GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |