Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 3/20 | 0.76 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.76 |
| ▸ | ESR1 | P03372 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.69 |
| ▸ | PGR | P06401 | 2/20 | 0.69 |
| ▸ | AR | P10275 | 2/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.69 |
| ▸ | SHBG | P04278 | 1/20 | 0.69 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.69 |
| ▸ | SNCA | P37840 | 1/20 | 0.69 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.69 |
| ▸ | UGT1A10 | Q9HAW8 | 1/20 | 0.69 |
| ▸ | STS | P08842 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2517551 | 1.00 | ABCC4 (0.76) | ABCC4ABCC1ESR1LMNAESR2 | |
| SCHEMBL345571 | 0.91 | STS (0.76) | ABCC4ABCC1ESR1LMNAESR2 | |
| SCHEMBL6440061 | 0.91 | KDM4E (0.76) | ABCC4ABCC1ESR1LMNAESR2 | |
| SCHEMBL6369320 | 0.91 | STS (0.76) | ABCC4ABCC1ESR1LMNAESR2 | |
| SCHEMBL2522894 | 0.90 | ABCC4 (0.71) | ABCC4ABCC1ESR1LMNAESR2 | |
| SCHEMBL6369302 | 0.89 | ESR1 (0.66) | ABCC4ABCC1ESR1LMNAESR2 | |
| SCHEMBL8214049 | 0.89 | ESR1 (0.66) | ABCC4ABCC1ESR1LMNAESR2 | |
| SCHEMBL3371578 | 0.89 | ESR1 (0.66) | ABCC4ABCC1ESR1LMNAESR2 | |
| SCHEMBL3369399 | 0.89 | ESR1 (0.66) | ABCC4ABCC1ESR1LMNAESR2 | |
| SCHEMBL9397340 | 0.88 | ESR1 (0.77) | ABCC4ABCC1ESR1LMNAESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275935-A1 | Estratriene Derivatives | CRYPTOPHARMA PTY LTD (AU) | 2007-11-29 | — | — | US | disclosed |
| EP-1625143-A1 | ESTRATRIENE DERIVATIVES | Cryptopharma Pty Ltd (AU) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004101595-A1 | ESTRATRIENE DERIVATIVES | CRYPTOPHARMA PTY LTD (AU) | 2004-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275935-A1 | Estratriene Derivatives | ESR2, ESRRB, NR3C2 | ABCC4 3799/4885ABCC1 3551/4885ESR1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.