Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 4/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | SCN1A | P35498 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25278732 | 0.89 | ESR1 (0.52) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL25283017 | 0.86 | ESR1 (0.54) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL25231397 | 0.86 | ESR1 (0.52) | PMP22ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL25285458 | 0.85 | ESR1 (0.56) | CYP3A4ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL16013155 | 0.82 | ESR1 (0.53) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL17685778 | 0.82 | ESR1 (0.53) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL16013154 | 0.82 | ESR1 (0.53) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL16154819 | 0.82 | ESR1 (0.53) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL22503890 | 0.82 | ESR1 (0.53) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL25708309 | 0.82 | ESR1 (0.50) | PMP22ESR1AKR1C4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452930-A1 | IONIZABLE AMINE AND ESTER LIPIDS AND LIPID NANOPARTICLES | Beam Therapeutics Inc. (US) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023121970-A1 | IONIZABLE AMINE AND ESTER LIPIDS AND LIPID NANOPARTICLES | BEAM THERAPEUTICS INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023121970-A1 | IONIZABLE AMINE AND ESTER LIPIDS AND LIPID NANOPARTICLES | BEAM THERAPEUTICS INC. (US) | 2023-06-29 | — | — | WO | disclosed |