Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.38 |
| ▸ | TRAP1 | Q12931 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CPS1 | P31327 | 2/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 4/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25274458 | 0.89 | TRAP1 (0.37) | PTGDR2TRAP1CPS1ABHD6FFAR1 | |
| SCHEMBL25232673 | 0.81 | ESR1 (0.46) | TRAP1ABHD6ESR1ESR2 | |
| SCHEMBL25233230 | 0.77 | TRAP1 (0.42) | TRAP1CPS1ABHD6ESR1ESR2 | |
| SCHEMBL29124891 | 0.77 | ESR2 (0.42) | TRAP1ALDH1A1CPS1ABHD6ESR1 | |
| SCHEMBL30666315 | 0.77 | ESR2 (0.42) | TRAP1ALDH1A1CPS1ABHD6ESR1 | |
| SCHEMBL38662452 | 0.76 | PTGDR2 (0.43) | PTGDR2ABHD6ESR1 | |
| SCHEMBL25424219 | 0.73 | RYR2 (0.44) | PTGDR2TRAP1CPS1FFAR1FFAR4 | |
| SCHEMBL38665323 | 0.72 | PTGDR2 (0.42) | PTGDR2TRAP1ALDH1A1ABHD6HSP90B1 | |
| SCHEMBL38662139 | 0.71 | PTGDR2 (0.41) | PTGDR2TRAP1HSP90B1ESR1 | |
| SCHEMBL25422546 | 0.71 | DPP4 (0.38) | PTGDR2TRAP1CPS1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024032782-A1 | VACCINE ADJUVANTS AND USES THEREOF | JACOBIO PHARMACEUTICALS CO.LTD. (CN) | 2024-02-15 | — | — | WO | disclosed |
| EP-4313962-A1 | NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF | Jacobio Pharmaceuticals Co., Ltd. (CN) | 2024-02-07 | — | — | EP | disclosed |
| WO-2023109942-A1 | COMPOUND-LINKER CONSTRUCTS COMPRISING NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |