Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13275271 | 0.85 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL3303677 | 0.85 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL282182 | 0.85 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL3303681 | 0.85 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL3346298 | 0.84 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL3349938 | 0.84 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL3346296 | 0.84 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL13275445 | 0.81 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL13275900 | 0.81 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL13275442 | 0.81 | HSD11B1 (0.32) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039503-B2 | Lapachone compounds and methods of use thereof | ARQULE, INC. (US) | 2011-10-18 | — | — | US | disclosed |