SCHEMBL2523519

SCHEMBL2523519

CCOc1ccc(F)cc1OCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.53
TDP1 Q9NUW8 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C19 P33261 1/20 0.53
MAPT P10636 4/20 0.46
KDM4E B2RXH2 1/20 0.46
GAA P10253 1/20 0.46
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.43
EGFR P00533 3/20 0.43
NPSR1 Q6W5P4 1/20 0.42
GLA P06280 1/20 0.42
HRH4 Q9H3N8 1/20 0.42
KDM1A O60341 2/20 0.42
RAB9A P51151 1/20 0.42
ATM Q13315 1/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18688122 0.90 L3MBTL1 (0.54) L3MBTL1TDP1CYP1A2CYP2D6CYP2C19
SCHEMBL12129028 0.90 KDM4E (0.59) L3MBTL1TDP1CYP1A2CYP2D6CYP2C19
SCHEMBL6906807 0.89 L3MBTL1 (0.45) L3MBTL1TDP1CYP1A2CYP2D6CYP2C19
SCHEMBL9631971 0.87 KMT2A (0.54) L3MBTL1TDP1CYP1A2CYP2D6CYP2C19
SCHEMBL9632496 0.87 L3MBTL1 (0.51) L3MBTL1TDP1CYP1A2CYP2D6CYP2C19
SCHEMBL9632943 0.87 L3MBTL1 (0.53) L3MBTL1TDP1CYP1A2CYP2D6CYP2C19
SCHEMBL4050101 0.86 L3MBTL1 (0.42) L3MBTL1TDP1CYP1A2CYP2D6CYP2C19
SCHEMBL4018504 0.86 L3MBTL1 (0.46) L3MBTL1TDP1CYP1A2CYP2D6CYP2C19
SCHEMBL1547577 0.84 L3MBTL1 (0.53) L3MBTL1TDP1CYP1A2CYP2D6CYP2C19
SCHEMBL1539296 0.84 L3MBTL1 (0.53) L3MBTL1TDP1CYP1A2CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8039552-B2 Process for producing propylene block copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-10-18 US disclosed
US-20100004395-A1 PROCESS FOR PRODUCING PROPYLENE BLOCK COPOLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-01-07 US disclosed
CN-101619151-A Process for producing propylene block copolymer SUMITOMO CHEMICAL CO 2010-01-06 CN disclosed