SCHEMBL25235490

SCHEMBL25235490

CCCNCC(O)COc1ccccc1C(=O)/C=C/c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 13/20 0.64
LMNA P02545 2/20 0.64
CYP1A2 P05177 2/20 0.64
CYP2D6 P10635 2/20 0.64
CYP3A4 P08684 2/20 0.64
KCNH2 Q12809 2/20 0.64
ADRB2 P07550 2/20 0.64
ADRB1 P08588 2/20 0.64
ADRB3 P13945 2/20 0.64
KCNK3 O14649 1/20 0.64
SLC22A1 O15245 1/20 0.64
ABCC9 O60706 1/20 0.64
KCNK2 O95069 1/20 0.64
ABCB11 O95342 1/20 0.64
ADRA2C P18825 1/20 0.64
SLC6A2 P23975 1/20 0.64
HTR2A P28223 1/20 0.64
HTR2C P28335 1/20 0.64
SLC6A4 P31645 1/20 0.64
ADRA1A P35348 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25202177 1.00 ABCB1 (0.64) ABCB1LMNACYP1A2CYP2D6CYP3A4
SCHEMBL30384033 1.00 ABCB1 (0.64) ABCB1LMNACYP1A2CYP2D6CYP3A4
SCHEMBL25283004 1.00 ABCB1 (0.64) ABCB1LMNACYP1A2CYP2D6CYP3A4
SCHEMBL25193926 1.00 ABCB1 (0.64) ABCB1LMNACYP1A2CYP2D6CYP3A4
Hydrochloric Acid SCHEMBL25192196 0.99 MEN1 (0.64) ABCB1LMNACYP1A2CYP2D6CYP3A4
SCHEMBL3440702 0.86 ABCB1 (0.51) ABCB1LMNACYP1A2CYP2D6CYP3A4
SCHEMBL30383779 0.86 ABCB1 (0.51) ABCB1LMNACYP1A2CYP2D6CYP3A4
SCHEMBL3440703 0.86 ABCB1 (0.51) ABCB1LMNACYP1A2CYP2D6CYP3A4
SCHEMBL10830262 0.85 ABCB1 (0.65) ABCB1LMNACYP1A2CYP2D6CYP3A4
SCHEMBL30382781 0.85 ABCB1 (0.65) ABCB1LMNACYP1A2CYP2D6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ABCB1 1289/4885LMNA 1180/4885CYP1A2 541/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ABCB1 3877/4885LMNA 1817/4885CYP1A2 1041/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ABCB1 3877/4885LMNA 1817/4885CYP1A2 1041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.