SCHEMBL25236243

SCHEMBL25236243

O=C(O)CCOc1cccc(/C=C/C(=O)c2ccc(-c3ccccc3)cc2)c1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BCHE P06276 6/20 0.56
MAOB P27338 2/20 0.53
ACHE P22303 5/20 0.51
MAOA P21397 1/20 0.50
CYSLTR2 Q9NS75 2/20 0.49
ALDH1A1 P00352 2/20 0.49
CYSLTR1 Q9Y271 1/20 0.49
LMNA P02545 1/20 0.49
THRB P10828 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
PPARA Q07869 1/20 0.49
RELA Q04206 1/20 0.49
KDM4E B2RXH2 1/20 0.49
PKM P14618 1/20 0.49
CYP1A1 P04798 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP1B1 Q16678 1/20 0.49
DHFR P00374 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25279152 1.00 BCHE (0.56) BCHEMAOBACHEMAOACYSLTR2
SCHEMBL30383059 1.00 BCHE (0.56) BCHEMAOBACHEMAOACYSLTR2
SCHEMBL30383171 1.00 BCHE (0.56) BCHEMAOBACHEMAOACYSLTR2
SCHEMBL25218020 0.93 BCHE (0.65) BCHEMAOBACHEMAOAALDH1A1
SCHEMBL31233116 0.93 BCHE (0.65) BCHEMAOBACHEMAOAALDH1A1
SCHEMBL25229347 0.93 BCHE (0.65) BCHEMAOBACHEMAOAALDH1A1
SCHEMBL30383438 0.93 BCHE (0.65) BCHEMAOBACHEMAOAALDH1A1
SCHEMBL25195492 0.89 BCHE (0.59) BCHEMAOBMAOACYSLTR2ALDH1A1
SCHEMBL25200452 0.89 BCHE (0.59) BCHEMAOBMAOACYSLTR2ALDH1A1
SCHEMBL25190942 0.89 BCHE (0.59) BCHEMAOBMAOACYSLTR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B BCHE 588/4885MAOB 1004/4885ACHE 806/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 BCHE 465/4885MAOB 2435/4885ACHE 656/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 BCHE 465/4885MAOB 2435/4885ACHE 656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.