Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3799108 | 0.98 | CA1 (0.55) | CA1CA2CA7CA9CA12 | |
| Hydrochloric Acid SCHEMBL20766163 | 0.95 | CA1 (0.52) | CA1CA2CA7CA9CA12 | |
| SCHEMBL7043985 | 0.83 | CA1 (0.55) | CA1CA2CA7CA9CA12 | |
| SCHEMBL19523638 | 0.82 | KDM4E (0.50) | ALDH1A1CYP3A4RAB9ATSHRLMNA | |
| SCHEMBL3152160 | 0.80 | CA1 (0.58) | CA1CA2CA7CA9CA12 | |
| SCHEMBL3976751 | 0.79 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL3241488 | 0.79 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1706121 | 0.79 | PDE2A (0.62) | TDP1MAPK1ALDH1A1CYP3A4PDE2A | |
| SCHEMBL9319281 | 0.78 | CA1 (0.55) | CA1CA2CA7CA9CA12 | |
| SCHEMBL677932 | 0.78 | CA1 (0.55) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109973-A1 | PEROVSKITE METAL HALIDE ZERO-DIMENSIONAL QUANTUM DOT COMPOSITE MATERIAL AND PREPARATION METHOD THEREFOR, AND USE OF ORGANIC AMINE SALT | 南开大学 | 2023-06-22 | — | — | WO | disclosed |
| CN-114149641-B | Perovskite metal halide zero-dimensional quantum dot/polymer composite material, preparation method thereof and application of organic amine salt | 南开大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-114369453-A | Perovskite metal halide zero-dimensional quantum dot composite material, preparation method thereof and application of organic amine salt | 南开大学 | 2022-04-19 | — | — | CN | disclosed |
| CN-114195650-A | Perovskite metal halide zero-dimensional quantum dot composite material, preparation method thereof and application of organic amine salt | 南开大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-114149641-A | Perovskite metal halide zero-dimensional quantum dot/polymer composite material, preparation method thereof and application of organic amine salt | 南开大学 | 2022-03-08 | — | — | CN | disclosed |