Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MPI | P34949 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 10/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.43 |
| ▸ | RELA | Q04206 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2525125 | 0.89 | KDM4E (0.50) | MAPTKDM4EKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL2523698 | 0.85 | MAPT (0.63) | MAPTKDM4EKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL2523696 | 0.83 | MAPT (0.46) | MAPTKDM4EKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL2521716 | 0.80 | KDM4E (0.53) | MAPTKDM4EKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL2521161 | 0.80 | MAPT (0.71) | MAPTKDM4EKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL2518215 | 0.80 | MAPT (0.71) | MAPTKDM4EKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL2518129 | 0.79 | MAPT (0.69) | MAPTKDM4EKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL5594397 | 0.76 | MAPT (0.77) | MAPTKDM4EKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL2523503 | 0.72 | KDM4E (0.50) | MAPTKDM4EKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL2525120 | 0.70 | KDM4E (0.50) | MAPTKDM4EKMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110251238-A1 | PPAR AGONIST COMPOSITIONS AND METHODS OF USE | BIOPHARMED (FR) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251238-A1 | PPAR AGONIST COMPOSITIONS AND METHODS OF USE | PPARA, PPARG, PPARD | MAPT 4323/4885KDM4E 4239/4885KMT2A 3167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.