SCHEMBL25237374

SCHEMBL25237374

COc1ccccc1C(=O)C=Cc1ccc(C(=O)O)cc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 4/20 0.83
XDH P47989 1/20 0.61
MAPT P10636 3/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
NPC1 O15118 1/20 0.59
RAB9A P51151 1/20 0.59
APP P05067 1/20 0.59
TNFRSF1A P19438 2/20 0.58
CXCL12 P48061 1/20 0.58
MKNK2 Q9HBH9 1/20 0.56
CYP3A4 P08684 2/20 0.56
ABCB1 P08183 1/20 0.56
MAOB P27338 3/20 0.55
ALDH1A1 P00352 1/20 0.55
HSPD1 P10809 1/20 0.55
HSPE1 P61604 1/20 0.55
CYP1B1 Q16678 1/20 0.55
BCHE P06276 1/20 0.55
NFKB1 P19838 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25198837 1.00 ABCG2 (0.83) ABCG2XDHMAPTMEN1KMT2A
SCHEMBL4254944 0.90 ABCG2 (0.90) ABCG2MAPTMEN1KMT2ANPC1
SCHEMBL4254947 0.90 ABCG2 (0.90) ABCG2MAPTMEN1KMT2ANPC1
SCHEMBL15631510 0.87 ABCG2 (0.91) ABCG2MAPTMEN1KMT2ANPC1
SCHEMBL20339098 0.85 ABCG2 (0.88) ABCG2XDHMAPTMEN1KMT2A
SCHEMBL20339099 0.85 ABCG2 (0.88) ABCG2XDHMAPTMEN1KMT2A
SCHEMBL25195139 0.85 ABCG2 (0.63) ABCG2XDHMAPTMEN1KMT2A
SCHEMBL25223431 0.85 ABCG2 (0.59) ABCG2MAPTKMT2ANPC1RAB9A
SCHEMBL25209312 0.85 ABCG2 (0.59) ABCG2MAPTKMT2ANPC1RAB9A
SCHEMBL25214393 0.85 ABCG2 (0.63) ABCG2XDHMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ABCG2 1606/4885XDH 1328/4885MAPT 3297/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885XDH 1963/4885MAPT 3512/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885XDH 1963/4885MAPT 3512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.