Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25235278 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2NPSR1LMNATSHRMAPK1 | |
| SCHEMBL14839559 | 0.78 | SLC6A2 (0.50) | HTR1A | |
| SCHEMBL29748355 | 0.78 | PRCP (0.35) | HTR2BADRA2AADRA2BADRA2C | |
| SCHEMBL24005410 | 0.78 | PRCP (0.35) | HTR2BADRA2AADRA2BADRA2C | |
| SCHEMBL29246605 | 0.78 | PRCP (0.35) | HTR2BADRA2AADRA2BADRA2C | |
| SCHEMBL30421244 | 0.78 | PRCP (0.35) | HTR2BADRA2AADRA2BADRA2C | |
| SCHEMBL28521149 | 0.78 | MEN1 (0.49) | MEN1KMT2AHTR2CATMHTR2A | |
| SCHEMBL28521153 | 0.78 | MEN1 (0.49) | MEN1KMT2AHTR2CATMHTR2A | |
| SCHEMBL25355022 | 0.77 | HTR2A (0.48) | MEN1KMT2AHTR2CATMHTR2A | |
| SCHEMBL25238785 | 0.77 | ATM (0.45) | SMN1; SMN2MEN1KMT2AHTR2CATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250099481-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. | 2025-03-27 | — | — | US | disclosed |
| WO-2023121713-A1 | BCL-2 INHIBITORS | NEW AVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250099481-A1 | BCL-2 INHIBITORS | BCL2, BCL2L1, BCL2L10 | SMN1; SMN2 2544/4885NPSR1 4336/4885LMNA 893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.